Jesus and Mo Wednesday

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The importance of RNA-Seq and next generation

I want to draw your attention to: Genomics researchers astonished to learn microarrays still exist. I especially like this comment from the author (jovialscientist) ...

In recent years, RNA sequencing (RNA-Seq) has been favoured over microarrays. This new technology, using next-generation sequencing, is slightly more accurate, and nations have recently declared war over which is the best aligner to use.

In a recent poll, 98% of researchers answered "next-generation sequencing" to every single question – even their name, age and job title. The new science of "sequence first, think later" has been coined "nextgenomics".

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New friends in New York

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Valley girl talk

Last summer we took a short drive through the San Fernando Valley on our way from Thousand Oaks to Griffith Park. I happened to mention "valley talk" ("uptalk") but none of us could do a good job of talking like a teenage girl from the valley.

That's a shame because now it looks like Valley girl speak is, like, on the rise! I believe it. Not only have I heard girls speak like this on the university campus here in Toronto but I've even heard this language in Ottawa and that's about as far away from California as you can get.

I hope my granddaughter and grandson don't grow up speaking like this. They live in Los Angeles.


Moon Unit Zappa Valley Girl by mrjyn

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Little Richie Dawkins

One thing that draws me to the ID movement is that it has the polite and understated ethic that science is supposed to have -- but does not have when the subject is evolution.

Stephen A. BatzerHere's a video that was posted today on Uncommon Descent by Salvador Cordova. Before watching it, read my post on: Why are Darwinists do uncivil?. It links to an IDiot post by Stephen A. Batzer where he complains about "Darwinists" being uncivil.

Here's one of the points that Batzer makes ...

Thought leaders in the Darwinian movement, such as Dawkins, Prothero, Shermer and so on, inculcate and advocate incivility by their own example. Look at the way biologist James Shapiro and philosopher Jerry Fodor have been treated. It's ugly.

The video was produced by Mike Booth. Decide for yourself if the evolution side of the debate behaves like the IDiots. (Apologies to Richard Dawkins for propagating this nonsense but people need to see the depths to which the Intelligent Design Community can sink.)


UPDATE: Denyse O'Leary has responded to this post [Huh? Actually, we thought Little Richie (Dawkins) was a special creation, just for us…]. She says, "Moran thinks it originated in the ID community. Unclear why because it’s really not about our usual questions and concerns." Actually I don't know anything about Mike Booth or whether he is a support of Intelligent Design Creationism. I looked, but I couldn't find anything. What I do know is that IDiots like Denyse O'Leary post the obnoxious video on their websites. O'Learly also says this about the video, "It’s also not a lot nastier than the old showman himself." I think I'll let intelligent people decide for themselves who is nastier. I'm glad that Denyse O'Leary at least acknowledges that the video she posted was nasty.

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Unchained Melody by The Rightous Brothers

Is it true that the music of the Baby Boomers is a whole lot better than the music of Generation-X or the Millennials (Generation-Y)? Of course it's true. Those whippernappers couldn't touch the best music of the 1960s.

Here's a song that makes my top ten list, although I will admit that it's only #374 on 500 Greatest Songs of All Time. I'm pretty sure this must be a mistake. Rolling Stone also seems to have made a mistake with #9.


(For some strange reason, my son and daughter don't seem to appreciate the music of my generation. I don't know where I went wrong.)

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Oops!

This is the view from the window just outside my office on the fifth floor.

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Jesus and Mo

See Jesus and Mo: Sept. 18, 2013

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Majority Of Americans Approve Of Sending Congress To Syria

From the Onion: Poll: Majority Of Americans Approve Of Sending Congress To Syria

WASHINGTON—As President Obama continues to push for a plan of limited military intervention in Syria, a new poll of Americans has found that though the nation remains wary over the prospect of becoming involved in another Middle Eastern war, the vast majority of U.S. citizens strongly approve of sending Congress to Syria.

The New York Times/CBS News poll showed that though just 1 in 4 Americans believe that the United States has a responsibility to intervene in the Syrian conflict, more than 90 percent of the public is convinced that putting all 535 representatives of the United States Congress on the ground in Syria—including Senate pro tempore Patrick Leahy, House Speaker John Boehner, House Majority Leader Eric Cantor, and House Minority Leader Nancy Pelosi, and, in fact, all current members of the House and Senate—is the best course of action at this time.

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Citing overwhelming support from the international community—including that of the Arab League, Turkey, and France, as well as Great Britain, Iraq, Iran, Russia, Japan, Mexico, China, and Canada, all of whom are reported to be unilaterally in favor of sending the U.S. Congress to Syria—the majority of survey respondents said they believe the United States should refocus its entire approach to Syria’s civil war on the ground deployment of U.S. senators and representatives, regardless of whether the Assad regime used chemical weapons or not.

Sounds like a good idea but shouldn't Barack Obama and John Kerry go with them?

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Goodbye Dumpster

Jerry Coyne posted this video and I thought it was so funny I just had to put it on my website blog.

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Get a Job: Dallas, Texas (USA)

The Chair of my department¹ asked me to post this job advertisement in case any biochemists might be interested. It's a challenging position in Dallas, Texas. You'll have plenty of opportunity to investigate some of the weirdest subjects in all of biology. All you really need is an inquisitive mind—with a few minor restrictions [Wanted: Young Creation Scientists].

ICR, together with the rest of the creation science movement, has made great strides in the last 40 years. In many areas, the superiority of the creation worldview has been clearly demonstrated. Even now, ICR is making exciting discoveries in the fields of biology and geology, and we have started new research initiatives in the field of astronomy. However, there is much work that still needs to be done, and this work is hindered by a lack of trained scientists.

Therefore, we appeal to any Bible-believing young person with an interest in science—have you considered cultivating that science interest for the glory of God?

Many young people choose careers for all the wrong reasons (e.g., maybe a college major is “easy” or they can earn a lot of money). Yet some choices in this area can have negative consequences later in life.What good is it to earn a large salary if your job is unfulfilling? Is it worth it to major in an easy field if you ultimately get a job that you dislike? Little wonder that so many adults are eager to retire from the workforce—they hate their jobs!

How much better to choose a career path that will bring ultimate fulfillment, a decision inspired by a God-given desire to work in a field that will bring glory to the Creator. Young Christian, if God has given you a desire to serve Him in a particular area, then consider His promptings. Maybe He is leading you to serve Him in the field of science. It may involve short-term sacrifice, but God’s best often requires hard work.

If you have an interest in science, then pursue it. An aptitude and a genuine love for science is a rare gift—maybe you can be the one to make a startling discovery or a life-changing advancement in the field. Maybe history will be different because of you. Perhaps you can be the one to finally break the evolutionary monopoly on our institutions of higher learning.

Of course, not everyone has an interest in science. God has given us all different gifts (1 Corinthians 12:4-7) and called us to different areas of service. But Christian young people might consider the challenge to seek God’s wisdom about their future, to consider His direction when they are making their career choices.

For those who do have an interest in science, we wish to offer a few words of advice. Work hard to get the best possible grades and push yourself to truly understand the material. When choosing a school, choose one with a rigorous academic program and a research program that truly interests you. Although you should not be dishonest about what you believe, it’s probably prudent to not draw attention to your creationist beliefs while you are a student, particularly if you are in a field that directly touches upon the origins controversy (such as paleontology, biology, or geology).

Given the increasing anti-Christian sentiment in society and the academic persecution in the secular universities, there may very well come a day when it will no longer be possible for a Bible-believing Christian to get an advanced degree in the natural sciences. Academically gifted young Christians should therefore “redeem the time” (Ephesians 5:16) before that door of opportunity closes.

They don't say how many letters of reference they need. They also don't mention salary. Something in the range of $100,000 - $120,000 would be typical for real scientists at a good school in Texas. ICR probably has to pay more in order to get the very best candidates.

Start-up funds are negotiable but you should probably ask for one million dollars to set up a decent lab. That's about the minimum you're going to need since your chances of getting NIH or NSF funding are pretty slim.

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1. He has a great sense of humor. I'm not sure if he wants to be identified by name on this blog but you can find him on our website under Justin Nodwell, Chair.

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PLANETARY STORIES LAUNCHES NEW ISSUE

Cover: Jim Garrison

New Pulp publisher Planetary Stories released their 28th free on-line issue. You can find it here.

This issue features new Planetary Stories authors, including "Incident on Titus Thirteen," a great mix of Space Opera, action and humor, by J Eckert Lytle and "Krax Delivered", action-packed
Space Opera by Joel Zartman. Plus tons more!

Go to www.planetarystories.com/PS28.htm for more.

Writers, Planetary Stories is hosting a flash fiction contest!
They are paying pro rates for stories.
Get more details here.

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Spontaneous Degradation of DNA

I heard a crash in my outer office. I knew what had happened. My cool space-filling model of DNA is 33 years old and it is spontaneously degrading as the plastic connectors become brittle. This is very, very, sad.

I don't think it can be replaced because I can't find anything similar on the internet. Besides, I figure it would cost over three thousand dollars at today's prices.

I can't bear to look at it anymore. It will have to go in the garbage.

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American Loons: #409 Jonathan Wells and #411 John West

Jonathan Wells has just been named to the Encyclopedia of American Loons: #409: Jonathan Wells. He joins another Discovery Institute Fellow, #411 John West.

Appallingly inane crackpot, infuriatingly dense, and reprehensibly dishonest, Wells’s lack of insight and inability to even pretend to begin to understand anything before he starts criticizing it based on personal dislike, is of almost epic proportions. Yet he continues to be shockingly influential.

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Less than ideally honest chucklehead, and a prime case of every strand of cognitive bias channeled into a single-minded force of rage against reality. West should not be underestimated, however, as he has made serious contribution to undermining science and education.

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Goodby Penny!

Beginning yesterday the Canadian penny is being removed from circulation.

Everyone is supposed to round off to the nearest nickle. That's means that things that used to cost 16 or 17 cents will now cost 15 cents and things that used to cost 18 or 19 cents will now cost 20 cents.

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Dramatic Irony

From Wikipedia [irony] ...

Irony (from the Ancient Greek εἰρωνεία eirōneía, meaning dissimulation or feigned ignorance) is a rhetorical device, literary technique, or situation in which there is an incongruity between the literal and the implied meaning....

In dramatic irony, the author causes a character to speak or act erroneously, out of ignorance of some portion of the truth of which the audience is aware. In other words, the audience knows the character is making a mistake, even as the character is making it. This technique highlights the importance of a particular truth by portraying a person who is strikingly unaware of it.

The funny thing about irony (and sarcasm) is that there are so many people who are irony-deficient. They just don't get it. They seem to be incapable of recognizing anything other than the literal meaning of a statement. Look at the example given in the Wikipedia article (right figure). Then look at yesterday's Jesus and Mo cartoon (below). Both are excellent examples of intended irony.

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What's Wrong with These Sentences?

Here's a short paragraph containing three sentences from my textbook (page 584). Is there anything wrong with any of these sentences?

Under physiological conditions, double-stranded DNA is thermodynamically much more stable than the separated strands and that explains why the double-stranded form predominates in vivo. However, the structure of localized regions of the double helix can sometimes be disrupted by unwinding. Such disruption occurs during DNA replication, repair, recombination, and transcription.

Having trouble seeing where I went wrong, according to some people? Check out this and this.

Oh, and don't forget this.

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Drive-Thru at Timmy's

It's been ages since I've posted anything about the Canadian institution known as Tim Hortons. Here's a photo from cheezeburger.

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[Hat Tip: David Schuller.]

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